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Blood transport links distant tissues

By UK A Level Biology · independent study · myAudience

Read the closed circulation loop in arrow order: body, vena cava, right atrium, tricuspid valve, right ventricle, pulmonary valve, pulmonary artery, lungs, pulmonary vein, left atrium, mitral valve, left ventricle, aortic valve, aorta and body. Arteries lead away from the heart, regardless of oxygen content. The schematic Bohr curves compare saturation at equal oxygen partial pressure; elevated carbon dioxide favours unloading. Cardiac output is 4.68 dm³ per minute for the supplied example, not the sum of both ventricles.

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Blood transport links distant tissues

Blood circulation moves substances between organs. The heart generates pressure differences, while valves support one-way movement. Arteries, veins and capillaries have structures suited to different pressures and exchange roles; artery does not always mean oxygenated.

Haemoglobin binds oxygen cooperatively. Conditions in active tissues can favour unloading, including increased carbon dioxide. At capillary beds, pressure and water-potential differences contribute to tissue-fluid movement, with lymphatic drainage returning fluid to circulation.

Increasing carbon dioxide can shift the oxyhaemoglobin curve toward easier unloading at a given oxygen partial pressure, the Bohr effect. Tissue-fluid formation depends on pressure differences and the effects of plasma proteins on water potential; blood cells and most large proteins remain in circulation. Lymph drainage returns excess fluid. Cardiac-output calculations multiply volume per beat by beats per minute, so units explain why 4,680 cm³/min equals 4.68 dm³/min rather than 4.68 cm³/min.

Worked example: Heart rate is 72 beats per minute and stroke volume is 65 cm³. Calculate cardiac output.

Output = rate × volume per beat.

72 × 65 = 4680 cm³ per minute.

Answer: 4.68 dm³ per minute.

Check your understanding: Which artery carries blood from the heart toward the lungs?

Answer: The pulmonary artery.

Why: It carries blood away from the heart even though that blood has relatively low oxygen content.

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